Duodenal ulcer attributed to a chronic, severe and quite common gastrointestinal diseases. According to studies, it is ill to ten percent of the world's population. And they note that the more susceptible to the disease men than women, and as for age, ulcer manifests itself most often to thirty or forty years. Although, of course, you can get buy amoxil online sick at any age and without regard to gender.
Signs of duodenal ulcers include the appearance of the defect (in the form of ulceration) on the gastric mucosa directly or duodenum, which is characterized by impaired and distinctly delayed healing process. This defect, depending on the severity of the disease, can affect the region of a few millimeters to several centimeters same. It was noted that the ulcer formed in the four times more often in the duodenum than in the stomach. Less noted ulceration of the mucous both bodies - then diagnosed with concomitant gastric ulcer and duodenal ulcer. In contrast to the mucosal lesions in the form of erosion duodenal ulcer always heal with scar tissue formation.
More often than duodenal ulcer occurs as a consequence of existing gastritis (ie, inflammation of the stomach lining) or duodenitis (inflammation in the lining of the duodenum). These conditions are often associated with the ingestion of human activity and the bacterium Helicobacter Pylori. Also, the causes of the disease include increased acidity: humans, having an increased sensitivity of the mucous duodenum pepsin and acid can cause its transformation, and consequently, occurrence of ulcers. Can provoke a disease and receiving individual drugs - often inflammatory (aspirin, diclofenac, ibuprofen, and the like), since these drugs can erode the mucosa.
If the disease is caused by Helicobacter Pylori activities may well happen infestation of man by man, in particular in close and prolonged contact, kissing. The source of infection ulcer can become sick and personal belongings: dishes, linens and towels, which he enjoyed.
Provocateur disease may make smoking, love habits and an unhealthy lifestyle with irregular meals. It was also observed that the risk of duodenal ulcer can increase in people who are forced to work night shifts - according to the research, in this case, your risk increases by fifty percent. An important role in the development of the disease may also play a bad heredity, congenital characteristics of the organism and severe stress (ulcers can often be observed in people with "nervous" professions).
Proceeds the disease and is characterized by long periods of exacerbation and remission ulcer, severity of the disease may depend on the age and sex of the sick, the season and the stage of the disease. Exacerbations are associated with the seasons of the year - the highest number of acute conditions are recorded in the periods of spring and autumn. In the acute phase the disease can last from one week to several months almost. Combined gastric and duodenal ulcers can occur over time, ie the first patient diagnosed an ulcer in the duodenum, and then, years later, it is added, and gastric ulcer. In some rare cases, patients may show multiple ulcer.
If we talk about the symptoms of duodenal ulcers, the main - it's a pain, and the onset of the disease (or periods of exacerbation) is characterized by severe pain, but this may occur less pronounced pain symptoms. Localized pain is usually in the upper abdomen - in the stomach, or slightly to the right from the middle. But there may be and retrosternal pain (usually in the presence of ulcers, duodenal bulb to change the gatekeeper) or pain may occur abruptly gave back. Approximately one third of patients said about strong pains of a different nature - they can be pecking and dull, aching and as fights, the rest of the pain less severe. Painful attack can pass through the twenty to thirty minutes or go on for several hours. Often the pain may go away after a meal, and patients often try to "seize" the unpleasant symptoms, but sometimes the pain comes and after a meal, along with a feeling of heaviness in the stomach.
With the development of peptic ulcer disease suggests frequent nocturnal pain and hungry. Hunger may occur in about six or seven hours after the last meal. To remove them you can usually after drinking milk or eat. It may also be a feeling of urgent need something to eat within a short time after eating. About eighty percent of the patients reported that they wake up at night from the pain. This is because during the night the acidity increases - the highest amount of acid secretion is produced at about two o'clock. About fifty percent of patients complain of constipation related malaise - they may be the result of a violation intestinal motility, and triggered by medication.
Another common symptom of duodenal ulcer disease called heartburn - a characteristic burning sensation behind the breastbone, near the neck that occurs because the stomach contents into the esophagus. Symptoms of inflammation of the duodenum often include bloating, belching, flatulence, nausea. vomiting may occur at the peak of pain, after which the pain can be reduced, and the patient feels relief.
However, it happens that the symptoms of an ulcer does not show itself, the disease is completely asymptomatic - in a latent form of the disease often suffer aggravation of elderly patients.
In addition to discomfort, peptic ulcer disease, and could face more complications, the most common of which include bleeding, which manifests itself in the form of blood in the stool or vomit. Internal bleeding is very dangerous possibility of death - to find blood, you need to immediately contact a doctor!
Sometimes blood can be detected only on circumstantial evidence: the feces becomes almost black in color, this indicates a weak bleeding, which, however, requires a consultation with a physician. Another dangerous consequence is the inflammation of the duodenum ulcer perforation. Duodenal wall integrity is violated, there is a hole through which its contents into the peritoneal cavity, causing peritonitis - abdominal infection, a condition directly life-threatening patient. This aggravation is characterized by very severe pain, combined with deteriorating health and flatulence. In this case, it is important to seek medical attention at once - in the first hours after the deterioration. Since peritonitis treated exclusively by surgery, and lack of treatment leads directly to the patient's death. Scars are formed in situ ulceration may cause obstruction, which is also a severe condition. The result is a duodenal ulcer and duodenal bulb bulbit (otherwise it is called chronic duodenitis) - the disease occurs when a large amount of acid from the stomach enters the duodenum, the symptoms are similar to those observed during the plague.
By the dangerous consequences in the form of complications of peptic ulcer disease and malignancy refers, ie the transformation of the disease into a malignant tumor, defined as cancer of the duodenum. As with peptic ulcer disease, pain is the main and most early symptom of duodenal cancer (along with anorexia, heartburn, weakness, and weight loss) - aching pain often are permanent and have no connection with the meal.
Peptic ulcer disease, identified in children usually occurs less seriously than in adults and provides significantly fewer complications.